Benefit Risk Evaluation Assessor – £46,160 - £51,666 p.a. + benefits

Job summary

We are currently looking for a Benefit Risk Evaluation Assessor to join our Oncology, Haematology, and Thrombotic disease team, part of Benefit Risk Evaluation I within the Safety & Surveillance group.

This is a full-time opportunity, on a permanent basis. The role will be based in 10 South Colonnade, Canary Wharf London, E14 4PU.

Government departments and agencies are working towards implementing a minimum 60% attendance in office sites.

We are currently implementing a flexible, hybrid way of working, with a minimum of 8 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business. Attendance on site is driven by business needs so depending on the nature of the role, this can flex up to 12 days a month, with the remainder of time worked either remotely or in the office. Some roles will need to be on site more regularly.

Who are we?

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.

The Safety and Surveillance Group brings together into a single integrated structure devices and medicines safety expertise with enforcement capabilities. These functions are supported by our data and evidence generating capabilities complementing our signal generating capabilities produced via the new Safety Connect System.

Safety remains at the heart of our decision making. As such the core objective of the Safety & Surveillance Group is to protect the public from risks associated with medicines and medical devices by:

• Ensuring a world class, comprehensive vigilance system that can promptly detect and monitor signals across the product life cycle.

• Evaluating the balance of benefits and risks for medicines and medical devices, assessing signals, and developing effective and measurable risk mitigation measures.

• Deploying innovative interventions to reduce the criminal threat.

• Exploiting data and embracing new technologies to develop the evidence to support our actions and understand their impact.

Job description

The Oncology, Haematology, and Thrombotic disease team monitors safety of medicines and medical devices across these therapy areas. A significant focus of the team is to support approval of novel therapies through effective risk management, assessing plans for further characterisation post-marketing of potential safety concerns and maintaining product licences, ensuring effective minimisation of risks as new information on the safety of the products in our portfolio emerges.

What’s the role?

The core purpose of this role is to provide robust benefit risk assessments and review safety signals using data from a range of sources and technical, scientific, clinical, and regulatory knowledge and/or practical experience. Benefit risk assessors are responsible for engaging with a range of stakeholders including patients and the public to make timely and robust benefit-risk assessments and recommend safety actions and risk mitigations that are outcome focused.

Benefit/risk assessors are flexible according to business needs and work across therapeutic teams and the wider agency and the health and social care system to respond promptly to potential safety issues and protect patient safety.

All benefit risk roles require working flexibly to perform and contribute to benefit risk assessments across all medicine and medical device products as required.

Key responsibilities:

• Conduct robust assessments regarding medical devices and medicinal products in relation to emerging safety signals utilising a range of data sources.

• Be proactive in engaging with all stakeholders including patients and the public, health care professionals and companies to complete benefit risk evaluation assessments.

• Recommend timely and proportionate regulatory actions to enhance benefit and mitigate potential residual patient safety risks; this may include the development of impactful safety messages.

• Work in a matrix way to conduct benefit risk assessments, and as required assess clinical investigation applications, Exceptional Use Authorisations, Medicinal Product Variations, Risk Management Plans to set deadlines.

• Keep accurate records of benefit risk assessments and decisions as required.

• Contribute to and lead projects across the product life cycle to ensure compliance with regulations and contribute to assessing the impact of regulatory decisions on protecting patients and ensuring public health.

Who are we looking for?

Our successful candidate will have the following:

Behaviours

• Communicating and influencing - Communicate in a straightforward, honest, and engaging manner, choosing appropriate styles to maximise understanding and impact. Ensure communication has a clear purpose and takes into account people’s individual needs. Share information as appropriate and check understanding.

• Making Effective Decisions - Display confidence when making difficult decisions, even if they prove to be unpopular. Consult with others to ensure the potential impacts on end users have been considered. Gain a clear understanding of stakeholder’s needs and expectations. Act to prevent problems and provide solutions.

Experience

• Proven understanding of risk management principles to reduce harm (direct or indirect).

• Technical knowledge and/or practical experience of a range of medical devices and/or medicines within a therapeutic area

• Proven experience of managing complex projects to agreed milestones, managing conflicting priorities and the work of others.

• Proven experience in conducting benefit risk evaluations of medical devices and or medicines is desirable

Technical

• Degree or equivalent qualification in a related discipline (such as physical and/or biological sciences, pharmacy, engineering, or a relevant healthcare qualification)

• Previous relevant experience such as healthcare, medical device or medicinal product manufacturing, regulatory environment, clinical research or equivalent is desirable.

Person specification

Method of assessment: A=Application, I=Interview

Behaviour Criteria:

• Communicating and Influencing (A, I)

• Making Effective Decisions (A, I)

Experience Criteria:

• Proven understanding of risk management principles to reduce harm (direct or indirect). (A, I)

• Technical knowledge and/or practical experience of a range of medical devices and/or medicines within a therapeutic area (A, I)

• Proven experience of managing complex projects to agreed milestones, managing conflicting priorities and the work of others. (A, I)

• Proven experience in conducting benefit risk evaluations of medical devices and or medicines is desirable (A, I)

Technical Criteria:

• Degree or equivalent qualification in a related discipline (such as physical and/or biological sciences, pharmacy, engineering, or a relevant healthcare qualification) (A, I)

• Previous relevant experience such as healthcare, medical device or medicinal product manufacturing, regulatory environment, clinical research or equivalent is desirable. (A, I)

If you would like to find out more about this fantastic opportunity, please read our Job Description and Person Specification!

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Benefits

Alongside your salary of £46,160, Medicines and Healthcare Products Regulatory Agency contributes £13,372 towards you being a member of the Civil Service Defined Benefit Pension scheme. Find out what benefits a Civil Service Pension provides.

• Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays
• Privilege Leave: 1 day
• Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff
• Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay
• Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service
• Civil Service Pension Scheme. Please see the link for further information http://www.civilservicepensionscheme.org.uk/ For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666
• Flexible working to ensure staff maintain a healthy work-life balance
• Interest free season ticket loan or bike loan
• Employee Assistance Services and access to the Civil Service Benevolent Fund
• Eligibility to join Motoring , Boundless by CSMA
• Variety of staff and Civil Service clubs
• On-going learning and development

Things you need to know

Artificial intelligence

Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance (opens in a new window) for more information on appropriate and inappropriate use.

Selection process details

We use the Civil Service Success Profiles to assess our candidates, find out more here.

• Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.

• Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles.

In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of Experience criteria.

Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the competency-based answers provided- ensure you have read these thoroughly and allow sufficient time. You can view the competencies for this role in the job description.

If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible.

Closing date: 31 May 2026

Shortlisting date: 03 June 2026

Interview date: 16 & 17 June 2026

If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk

Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available here.

Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete basic personnel security standard checks.

Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include:

• Laboratory-based roles working directly with known pathogens

• Maintenance roles, particularly those required to work in laboratory settings

• Roles that involve visiting other establishments where vaccination is required

• Roles required to travel overseas where specific vaccination may be required.

Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government.

Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility here.

Individuals appointed on level transfer will retain their existing salary and are responsible for ensuring they fully understand the financial implications of any potential move and the impact (if any) on their terms. If an individual is in any doubt, they should seek clarification before accepting a job offer.

Staff joining on promotion will receive up to a 10% increase of their current basic salary, or the pay band minimum, whichever is the greater.

The individual will not retain any allowances paid by the former department/Agency, unless there are special circumstances, such as a reserved right to those allowances on transfer.

Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact careers@mhra.gov.uk.

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should firstly contact careers@mhra.gov.uk

If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk

info@csc.gov.uk

Civil Service Commission

Room G/8

1 Horse Guards Road

London

SW1A 2HQ

Feedback will only be provided if you attend an interview or assessment.

Security

Successful candidates must undergo a criminal record check.People working with government assets must complete baseline personnel security standard (opens in new window) checks.

Nationality requirements

This job is broadly open to the following groups:

• UK nationals
• nationals of the Republic of Ireland
• nationals of Commonwealth countries who have the right to work in the UK
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the European Union Settlement Scheme (EUSS) (opens in a new window)
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)
• individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020
• Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service

Further information on nationality requirements (opens in a new window)

Working for the Civil Service

The Civil Service Code (opens in a new window) sets out the standards of behaviour expected of civil servants.

We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's recruitment principles (opens in a new window).The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.

Diversity and Inclusion

The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see theCivil Service People Plan (opens in a new window) and the Civil Service Diversity and Inclusion Strategy (opens in a new window).

Apply and further information

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Contact point for applicants

Job contact :

• Name : The Resourcing Team
• Email : Careers@mhra.gov.uk

Recruitment team

• Email : Careers@mhra.gov.uk

Further information

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at Careers@mhra.gov.uk, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - info@csc.gov.uk - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ