Head of Vigilance Development - £81,000-£117,800 p.a. + benefits

Job summary

We are currently looking for a Head of Vigilance Development to join our Patient Safety Monitoring Function within the Safety & Surveillance group.

This is a full-time opportunity, on a permanent basis. The role will be based in 10 South Colonnade, Canary Wharf London, E14 4PU.

Who are we?

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.

The Safety and Surveillance Group brings together into a single integrated structure devices and medicines safety expertise with enforcement capabilities. These functions will be supported by our data and evidence generating capabilities complementing our signal generating capabilities produced via the Safety Connect System.

As such the central mission of the Safety & Surveillance portfolio is to protect the public from risks associated with medicines and medical devices by:

• Ensuring a world class, comprehensive vigilance system that can promptly detect and monitor signals across the product life cycle

• Evaluating the benefit risk of signals and developing effective and measurable risk mitigation measures

• Deploying innovative interventions to reduce the criminal threat

• Exploiting data and embracing new technologies to develop the evidence to support our actions and understand their impact

The Patient Safety Monitoring Function is responsible for developing and delivering a world class vigilance system to detect and monitor safety signals for medicines, medical devices, vaccines and blood products.

Job description

What’s the role?

The post holder will lead development of the MHRA vigilance system, including vigilance system transformation work, to ensure continuous improvement of joined-up systems and processes for all medicinal product types. Accountable for key projects within the Patient Safety Monitoring Function and engagement with strategic stakeholders in the UK healthcare system for adverse incident data collection and signal management processes.

This role leads delivery of continuous vigilance systems improvements to support collection and assessment of reaction and adverse incidents. Systems under the role’s responsibility include the public facing Yellow Card scheme as well as industry reporting portals, such as reporting for pharmaceutical companies, device manufacturers and blood incidents.

The main objectives are to work across the Agency and Health network to ensure MHRA has the information necessary to assess potential harms from medicinal products and take appropriate regulatory action as swiftly as possible.

Key responsibilities:

• Lead the development and enhancement of Safety & Surveillance IT systems and processes for the Patient Safety Monitoring Function to ensure continual improvement and best use of available resources for adverse incident data management and signal management activities ensuring the quality management system for vigilance activities is updated in line with new and incoming procedures, technologies and legislation.

• Collaborate and build relationships across the Agency and the UK Health Family to ensure vigilance systems are integrated with appropriate data sets, data standards and terminologies.

• Accountable for setting strategic direction and leading delivery of key projects arising from Yellow Card strategy recommendations and stakeholder engagement, as directed by the Senior Leadership Group.

• Represent the Agency at stakeholder working groups to develop best practice recommendations and foster new alliances for adverse incident data collection and other vigilance activities.

Person specification

Who are we looking for?

Our successful candidate will have the following:

Experience

• Extensive experience of successfully managing and using large quantities of adverse incident data for evaluation and reporting, providing information on complex and technical matters.

Behaviours

• Leadership - Welcome and respond to views and challenges from others, despite any conflicting pressures to ignore or give in to them. Stand by, promote or defend own and team’s actions and decisions where needed. Seek out shared interests beyond own area of responsibility, understanding the extent of the impact actions have on the organisation. Inspire and motivate teams to be fully engaged in their work and dedicated to their role to create a culture of high performance and continuous improvement.

• Seeing the Big Picture - Ensure plans and activities in your area of work reflect wider Agency and government strategic priorities and communicate effectively with senior leaders to influence future strategies. Bring together views, perspectives and diverse needs of stakeholders to gain a broader understanding of the issues surrounding policies and activities.

Technical

• Detailed knowledge of the data standards, taxonomies and systems involved in the reporting and management of adverse incidents for the maintenance and performance of business processes within Patient Safety Monitoring.

• Strong knowledge and understanding of medicines and medical device regulation for post marketing surveillance.

Person Specification:

Method of assessment: A=Application, I=Interview

Behaviour Criteria:

• Seeing the Big Picture (A, I)

• Leadership (A, I)

• Communicating and Influencing (A, I)

Experience Criteria:

• Extensive experience of successfully managing and using large quantities of adverse incident data for evaluation and reporting, providing information on complex and technical matters. (A, I)

• Project management experience, demonstration of successful delivery of projects to agreed timescales and budgets with deliverables of high quality (A, I)

• Knowledge of both medicines and medical devices legislative landscape and associated data standards and terminologies (A, I)

• Extensive experience of working with international projects and with other international regulators to ensure collaborative working and delivery. (A, I)

• Experience working with innovative technologies to delivery benefits to vigilance systems (A, I)

Technical Criteria:

• Degree or equivalent qualification in a relevant discipline e.g., pharmacy, science, medical engineering, medical physics, biomaterials or healthcare professional qualification or equivalent qualifications or relevant work experience. (A)

• Detailed knowledge of the data standards, taxonomies and systems involved in the reporting and management of adverse incidents for the maintenance and performance of business processes within Patient Safety Monitoring. (A)

• Effective presentation and communication skills, including excellent writing skills for preparing and independently writing briefing / formal reports. (A)

• Strong knowledge and understanding of medicines and medical device regulation.(A)

Strengths Criteria

• Improver (I)

• Disciplined (I)

• Adaptable (I)

• Team Leader (I)

If you would like to find out more about this fantastic opportunity, please read our Job Description and Person Specification!

Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact careers@mhra.gov.uk

Benefits

Alongside your salary of £81,000, Medicines and Healthcare Products Regulatory Agency contributes £23,465 towards you being a member of the Civil Service Defined Benefit Pension scheme. Find out what benefits a Civil Service Pension provides.

• Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays
• Privilege Leave: 1 day
• Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff
• Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay
• Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service
• Civil Service Pension Scheme. Please see the link for further information http://www.civilservicepensionscheme.org.uk/ For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666
• Flexible working to ensure staff maintain a healthy work-life balance
• Interest free season ticket loan or bike loan
• Employee Assistance Services and access to the Civil Service Benevolent Fund
• Eligibility to join the Civil Service Motoring Association (CSMA)
• Variety of staff and Civil Service clubs
• On-going learning and development

Things you need to know

Artificial intelligence

Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance (opens in a new window) for more information on appropriate and inappropriate use.

Selection process details

The selection process:

We use the Civil Service Success Profiles to assess our candidates, find out more here.

• Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.

• Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles.

Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the competency-based answers provided- ensure you have read these thoroughly and allow sufficient time. You can view the competencies for this role in the job description.

Use of AI in Job Applications

Artificial Intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance for more information on appropriate and inappropriate use.

If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible.

Closing date: 19 February 2026

Shortlisting date: From 20 February 2026

Interview date: w/c 16 March 2026

If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk

Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available here.

Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete basic personnel security standard checks.

Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include:

• Laboratory-based roles working directly with known pathogens

• Maintenance roles, particularly those required to work in laboratory settings

• Roles that involve visiting other establishments where vaccination is required

• Roles required to travel overseas where specific vaccination may be required.

Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government.

Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility here.

Standard Cabinet Office rules on pay will apply to civil servants appointed on level transfer or promotion. Their salary will increase to the minimum of the SCS PB1 range or by a promotion award of up to 10% more than their current basic salary excluding all allowances (whichever is the greater).

Individuals appointed on level transfer will retain their existing basic salary excluding all allowances. You may be eligible for a non-consolidated annual bonus payment, subject to successful performance, in line with the Senior Civil Service pay arrangements. These are set annually within the guidelines laid down by the Cabinet Office.

Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact careers@mhra.gov.uk.

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should firstly contact careers@mhra.gov.uk

If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk

info@csc.gov.uk

Civil Service Commission

Room G/8

1 Horse Guards Road

London

SW1A 2HQ

Feedback will only be provided if you attend an interview or assessment.This role has a minimum assignment duration of 3 years. An assignment duration is the period of time a Senior Civil Servant is expected to remain in the same post to enable them to deliver on the agreed key business outcomes. The assignment duration also supports your career through building your depth of expertise.

As part of accepting this role you will be agreeing to the expected assignment duration set out above. This will not result in a contractual change to your terms and conditions. Please note this is an expectation only, it is not something which is written into your terms and conditions or indeed which the employing organisation or you are bound by. It will depend on your personal circumstances at a particular time and business needs, for example, would not preclude any absence like family friendly leave. It is nonetheless an important expectation, which is why we ask you to confirm you agree to the assignment duration set out above.

Security

Successful candidates must undergo a criminal record check.People working with government assets must complete baseline personnel security standard (opens in new window) checks.

Nationality requirements

This job is broadly open to the following groups:

• UK nationals
• nationals of the Republic of Ireland
• nationals of Commonwealth countries who have the right to work in the UK
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the European Union Settlement Scheme (EUSS) (opens in a new window)
• nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)
• individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020
• Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service

Further information on nationality requirements (opens in a new window)

Working for the Civil Service

The Civil Service Code (opens in a new window) sets out the standards of behaviour expected of civil servants.

We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's recruitment principles (opens in a new window).The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.

Diversity and Inclusion

The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see theCivil Service People Plan (opens in a new window) and the Civil Service Diversity and Inclusion Strategy (opens in a new window).

Apply and further information

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Contact point for applicants

Job contact :

• Name : The Resourcing Team
• Email : Careers@mhra.gov.uk

Recruitment team

• Email : Careers@mhra.gov.uk

Further information

In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at Careers@mhra.gov.uk, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - info@csc.gov.uk - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ