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<h4>Job summary</h4><p>We are currently looking for an <strong>Animal Technician Manager</strong> to join our <strong>Research and Development </strong>Function within the <strong>Scientific Research and Innovation </strong>group. </p><p>This is a <strong>full-time</strong> opportunity, on a <strong>permanent </strong>basis. The role will be based in South Mimms, Hertfordshire. </p><p><strong>Who are we?</strong></p><p>The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. </p><p>The Scientific Research and Innovation Group delivers public health impact, world-leading research innovation, and a unique proposition via an ambitious Science Strategy which will balance innovation against sustainability and affordability. It is divided into 6 sub-Groups, Innovation Accelerator, Clinical Investigations and Trials, Research and Development, Standards Lifecycle, Control Testing and Quality Assurance and Health &amp; Safety. </p><p>The SR&amp;I Research &amp; Development (R&amp;D) function delivers statutory mandated strategically aligned, sustainable and impactful Regulatory Scientific research that is applied primarily to biological reference materials development and medicines control testing and areas of international and national priority for future biological medicines. </p><p>Analytical and Biological Sciences (ABS) is a multi-laboratory, multi-disciplinary team of experts within R&amp;D. Both in vitro and in vivo methods are used to deliver practical laboratory analysis, experimentation and expertise aligned the Agency objectives. Biological services, within ABS supports three Functions of SR&amp;I; Standards Lifecycle, Control Testing and R&amp;D in all aspects of in vivo science. The facility is provisioned to manage activities with a wide species including at different biocontainment levels up to and including containment level 3 (CL3) and Specified Animal Pathogen Order 4 (SAPO4). A highly trained and professional technical team care for the animals and perform the scientific procedures, underpinned by a specialist support team, ensuring the highest standards of animal welfare are always maintained. </p><h4>Job description</h4><p><strong>What’s the role?</strong></p><p>The post holder’s main responsibilities relate to the operation and management of studies within the Specified Animal Pathogen Order 4 (SAPO4) facility in addition to lower containment studies. The role holder actively contributes to the management, performance, and practical delivery of the in<em>-vivo</em> functions to support the scientific activities of the Agency including the care and welfare of a variety of animal species, including non-human primates (NHPs) housed in the biological services facility in support of the Agency programmes of work that require<em> in- vivo</em> models. </p><p>All responsibilities are performed in accordance with relevant Standard Operating Procedures, Codes of Practice and appropriate legislation and regulatory guidelines: </p><ul><li>Compliance with Animals (Scientific Procedures) Act 1986 (ASPA). </li></ul><ul><li>Compliance with Quality Standard ISO/IEC 17025. </li></ul><ul><li>Compliance with local Health and Safety Codes of Practice. </li></ul><p>Security Clearance must be obtained for this position, which requires 5 years’ UK residency. </p><p><strong>Key responsibilities:</strong></p><ul><li>Organisation and supervision of staff assigned to work in the managed area, including the provision of training, on-going competency, and continual professional development </li></ul><ul><li>Line Management duties for staff </li></ul><ul><li>Responsible for Health and Safety within the managed area </li></ul><ul><li>Department Quality Champion responsible for compliance with Quality standards e.g. ISO17025 </li></ul><p><strong>Who are we looking for?</strong></p><p>Our successful candidate will have: </p><ul><li>Experience of supervising/managing a discrete area within an animal laboratory facility. </li></ul><ul><li>Experience of organising, supervising, and training staff to meet operational, quality and health and safety requirements. </li></ul><ul><li>Considerable experience within the animal research field including on a range of species. </li></ul><ul><li>Minimal professional qualification of Membership of the Institute of Animal Technology (MIAT), or relevant equivalent (Registered Animal Technician status (RAnTech) is desirable). </li></ul><ul><li>Good knowledge of ASPA legislation, and relevant sections (in detail) of the Guidance, along with how the regulations are implemented in practice. </li></ul><h4>Person specification</h4><p><strong>Method of assessment: A=Application, I=Interview </strong></p><p><strong>Behaviour Criteria:</strong></p><ul><li>Leadership <strong>(A, I)</strong></li></ul><ul><li>Changing and Improving <strong>(I)</strong></li></ul><ul><li>Seeing the Big Picture <strong>(I)</strong></li></ul><p><strong>Experience Criteria:</strong></p><ul><li>Experience of supervising/managing a discrete area within an animal laboratory facility <strong>(A, I)</strong></li></ul><ul><li>Experience of organising, supervising, and training staff to meet operational, quality and health and safety requirements <strong>(A, I)</strong></li></ul><ul><li>Considerable experience within the animal research field including on a range of species <strong>(A, I)</strong></li></ul><p><strong>Technical Criteria:</strong></p><ul><li>Minimal professional qualification of Membership of the Institute of Animal Technology (MIAT), or relevant equivalent (Registered Animal Technician status (RAnTech) is desirable) <strong>(A, I)</strong></li></ul><ul><li>Current or recent holder of a Personal Individual Licence with proven training and competency records for species and techniques <strong>(A, I)</strong></li></ul><ul><li>Good knowledge of ASPA legislation, and relevant sections (in detail) of the Guidance, along with how the regulations are implemented in practice <strong>(I)</strong></li></ul><ul><li>Up to date on developments in education and training on laboratory animal science and welfare, and up to date on Home Office licensing requirements <strong>(I)</strong></li></ul><p><strong>Strengths Criteria</strong></p><ul><li>Adaptable <strong>(I)</strong></li></ul><ul><li>Networker <strong>(I)</strong></li></ul><p>If you would like to find out more about this fantastic opportunity, <a href="https://mhra-gov.filecamp.com/uniq/SuiMpQCxHHaELndm.pdf" target="_blank">please read our Job Description and Person Specification</a>! </p><p><strong><em>Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact </em></strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong><em>careers@mhra.gov.uk</em></strong></a></p><h4>Benefits</h4>Alongside your salary of £46,160, Medicines and Healthcare Products Regulatory Agency contributes £13,372 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><br><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p>We use the Civil Service Success Profiles to assess our candidates, <a href="https://www.gov.uk/government/publications/success-profiles" target="_blank">find out more here</a>. </p><ul><li>Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. <em>Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.</em></li></ul><ul><li>Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. </li></ul><p>In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of <strong>Experience of organising, supervising, and training staff to meet operational, quality and health and safety requirements.</strong></p><p><strong>If you require any disability related adjustments at any point during the process, please contact </strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong>careers@mhra.gov.uk</strong></a><strong> as soon as possible.</strong></p><p>Closing date: 13th February 2026 </p><p>Shortlisting date: from 16th February 2026 </p><p>Interview date: from 24th February 2026 </p><p>If you need assistance applying for this role or have any other questions, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a></p><p>Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available <a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">here</a>. </p><p>Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard?_ga=2.149328757.2118900794.1613132232-433185063.1580991281" target="_blank">basic personnel security standard checks</a>. </p><p>Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include: </p><ul><li>Laboratory-based roles working directly with known pathogens </li></ul><ul><li>Maintenance roles, particularly those required to work in laboratory settings </li></ul><ul><li>Roles that involve visiting other establishments where vaccination is required </li></ul><ul><li>Roles required to travel overseas where specific vaccination may be required. </li></ul><p>Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government. </p><p>Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility <a href="https://www.childcarechoices.gov.uk/" target="_blank">here</a>. </p><p>Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a>. </p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.Successful candidates must meet the security requirements before they can be appointed. The level of security needed is <a href="https://www.gov.uk/government/publications/national-security-vetting-advice-for-people-who-are-being-vetted" target="_blank">security check (opens in a new window)</a>.<br><br><a href="https://www.gov.uk/government/publications/vetting-explained-and-our-vetting-charter/the-vetting-charter" target="_blank">See our vetting charter (opens in a new window)</a>.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

Medicines and Healthcare Products Regulatory Agency

Animal Technician Manager - £46,160 p.a. + benefits

<h4>Job summary</h4><p>We are currently looking for a <strong>Shipping Team Leader</strong> to join our <strong>Standards Lifecycle </strong>Function within the <strong>Scientific Research and Innovation </strong>group. </p><p>This is a <strong>full-time</strong> opportunity, on a <strong>permanent </strong>basis. The role will be based in South Mimms, Hertfordshire. </p><p><strong>Who are we?</strong></p><p>The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. </p><p>The Standards Lifecycle group is responsible for the development, manufacturing and distribution of biological reference reagents to life science customers and organisations across the globe. These reference reagents play a critical role in maintaining and improving the quality of medicines and diagnostics, vaccine manufacturing, and public health. </p><p>The Logistics Function, located within the Standards Lifecycle group, is responsible for import and export shipping operations of the MHRA. This includes fulfilment of customer orders, international collaboration projects, and support of global health emergencies. </p><h4>Job description</h4><p><strong>What’s the role?</strong></p><p>The Shipping Team Leader is responsible for the line management of the shipping team (4-5 staff) as well as liaising with customer service, inventory and scientific teams to support and improve day to day operations. </p><p>The shipping team is a courier and customer facing section that carries out picking and shipping of technically complex products to customers in more than 100 countries. The team works directly with customers and couriers to generate shipping documentation, provide guidance and find agile solutions to problems. </p><p><strong>Key responsibilities:</strong></p><ul><li>Delivery of shipping output and targets </li></ul><ul><li>Process control and continuous improvement </li></ul><ul><li>Compliance with H&amp;S policy and regulations within the working area </li></ul><ul><li>Team leadership </li></ul><p><strong>Who are we looking for?</strong></p><p>Our successful candidate will: </p><ul><li>Be able to make effective decisions, and show confidence in difficult or unpopular choices. </li></ul><ul><li>Manage a high-tempo team, motivating staff and reallocating work for changing demands. </li></ul><ul><li>Manage a quality service, balancing customer needs against quality, policy, and regulatory requirements. </li></ul><ul><li>Have experience working in an international customer-facing logistics environment (e.g. biological, pharmaceutical, and ABP). </li></ul><ul><li>Be experienced and qualified in the shipping of dangerous goods by air. </li></ul><h4>Person specification</h4><p><strong>Method of assessment: A=Application, I=Interview </strong></p><p><strong>Behaviour Criteria:</strong></p><ul><li>Making Effective Decisions <strong>(A, I)</strong></li></ul><ul><li>Managing a Quality Service <strong>(A, I)</strong></li></ul><ul><li>Delivering at Pace <strong>(A, I)</strong></li></ul><p><strong>Experience Criteria:</strong></p><ul><li>Experience working in an international customer facing logistics environment with adherence to all the associated regulations <strong>(A, I)</strong></li></ul><ul><li>Understanding of customs regulations and paperwork particularly biological goods <strong>(A, I)</strong></li></ul><ul><li>Experience of shipping of dangerous goods especially class 6.2 <strong>(A, I)</strong></li></ul><ul><li>Experience working in a quality regulated environment e.g. ISO9001, GMP/GDP <strong>(I)</strong></li></ul><p><strong>Technical Criteria:</strong></p><ul><li>Degree-level or equivalent experience in internal shipping/logistics (Essential) <strong>(A, I)</strong></li></ul><ul><li>Dangerous Good regulations knowledge, including either current or previous holding of CAA certification for shipping of dangerous goods by air <strong>(A, I)</strong></li></ul><ul><li>Good IT literacy and use of MS Office, ERP systems and similar software <strong>(A, I)</strong></li></ul><p><strong>Strengths Criteria</strong></p><ul><li>Motivator <strong>(I)</strong></li></ul><ul><li>Problem Solver <strong>(I)</strong></li></ul><ul><li>Analytical <strong>(I)</strong></li></ul><ul><li>Team Leader <strong>(I)</strong></li></ul><p>If you would like to find out more about this fantastic opportunity, <a href="https://mhra-gov.filecamp.com/uniq/oiOLK49gAo92nF4x.pdf" target="_blank">please read our Job Description and Person Specification</a>! </p><p><strong><em>Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact </em></strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong><em>careers@mhra.gov.uk</em></strong></a></p><h4>Benefits</h4>Alongside your salary of £37,456, Medicines and Healthcare Products Regulatory Agency contributes £10,851 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p>We use the Civil Service Success Profiles to assess our candidates, <a href="https://www.gov.uk/government/publications/success-profiles" target="_blank">find out more here</a>. </p><ul><li>Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. <em>Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.</em></li></ul><ul><li>Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. </li></ul><p>In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of <strong>Experience working in an international customer facing logistics environment with adherence to all the associated regulations</strong> and <strong>Experience of shipping of dangerous goods especially class 6.2.</strong></p><p><strong>If you require any disability related adjustments at any point during the process, please contact </strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong>careers@mhra.gov.uk</strong></a><strong> as soon as possible.</strong></p><p>Closing date: 22nd January </p><p>Shortlisting date: from 26th January </p><p>Interview date: from 2nd February </p><p>If you need assistance applying for this role or have any other questions, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a></p><p>Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available <a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">here</a>. </p><p>Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard?_ga=2.149328757.2118900794.1613132232-433185063.1580991281" target="_blank">basic personnel security standard checks</a>. </p><p>Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include: </p><ul><li>Laboratory-based roles working directly with known pathogens </li></ul><ul><li>Maintenance roles, particularly those required to work in laboratory settings </li></ul><ul><li>Roles that involve visiting other establishments where vaccination is required </li></ul><ul><li>Roles required to travel overseas where specific vaccination may be required. </li></ul><p>Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government. </p><p>Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility <a href="https://www.childcarechoices.gov.uk/" target="_blank">here</a>. </p><p>Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a>. </p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

Shipping Team Leader - £37,456 p.a. + benefits

Senior Scientist - £46,160 p.a. + benefits

<h4>Job summary</h4><p><strong>Funding notes</strong></p><p>The studentship is fully funded for 4 years and is only available for students eligible for home UK fees. Applicants must have either already obtained or be predicted to secure a first-class MSci degree (at least 2:1) or a BSc (at least a merit) plus an MSc (at least 2:1) in a relevant subject or international equivalents of the relevant first degree and the Masters’ degree, to meet the entry requirements. UCL actively supports equality, diversity and inclusion and encourages applications from all sections of society. Applications from candidates under-represented within our research student community: BAME British applicants, applicants with disabilities and older applicants are strongly encouraged.</p><p>As a candidate you will be a motivated individual with a keen interest in undertaking research in the field of immunotherapy.</p><p><strong>Project description</strong></p><p>A 4-year full-time PhD studentship is available from October 2026 in Biotherapeutics and Advanced Therapies Team within the Science, Research and Innovation operational group (SR&amp;I) of the Medicines and Healthcare Products Regulatory Agency (MHRA) in collaboration with the UCL Department of Chemistry. The student will be required to complete two 3-month rotations in the wider Agency, within their first year allowing them to gain unique insight into public health research.</p><p>The project will be supervised by Dr Deepa Rajagopal and Dr. Sandrine Vessillier at MHRA and Professor Vijay Chudasama at UCL. The studentship is anticipated to commence 1st October 2026. The studentship will offer a yearly stipend, currently £22,780 and reviewed annually.</p><h4>Job description</h4><p><strong>About the Project</strong></p><p>Chimeric antigen receptor (CAR)-T cell therapy has shown great success in treating relapsed or refractory blood cancers, with several clinically approved treatments. However, current CAR-T therapies are associated with toxicological challenges, additionally involve complex, costly GMP manufacturing processes, and are associated with potential risks of introduction of viral components. The ErbB family of receptors, including epidermal growth factor receptor (EGFR), ErbB2, ErbB3, and ErbB4, play a crucial role in the development and progression of various cancers. Building up on the global success of the Covid-19 mRNA vaccine, this multi-disciplinary project will investigate mRNA-based in vivo CAR T-cell generation as a potential new approach for targeting T-cells for generation of efficient anti-tumour responses to gain an understanding of the immunotoxicological profile. The proposed project aims to leverage the mRNA platform to assess feasibility of in vivo reprogramming of circulating T-cells with a second- generation, pan ErbB-specific CAR (bearing the promiscuous ErbB ligand) for cancer immunotherapy, evaluating both anti-tumour efficacy and immunotoxicity. The in vivo approach will additionally employ targeting antibodies (Abs) to functionalise the mRNA lipid nanoparticles (LNPs) to facilitate uptake and targeted mRNA expression for in vivo therapeutic CAR T-cell induction. Recent studies indicate that the in vivo targeting approach produced CAR-T cells with similar anti-tumour activity to conventional CAR-T-cells and potential therapeutic benefit has been observed in disease conditions such as inflammatory cardiac fibrosis.</p><p>The successful candidate will acquire knowledge, expertise with training in a diverse range of laboratory techniques including LNP manufacture and functionalisation for selective targeting; in vitro, ex vivo and in vivo assays for therapeutic efficacy; and toxicological evaluation incorporating cellular, molecular biological and flowcytometry based assays. Furthermore, the student will benefit from the multidisciplinary expertise and supervision of Dr. Deepa Rajagopal, Dr. Sandrine Vessillier, Dr Christopher van der Walle (MHRA) and Professor Vijay Chudasama (UCL), gaining access to multiple laboratories and facilities across the two sites.</p><p>The candidate will also gain unique access to both UCL and MHRA / Civil Service training courses and be encouraged to present their work at both national and international conferences.</p><p><strong>Main Methods, Techniques and skills to be employed:</strong></p><ul><li>Molecular cloning, in vitro transcription assays, mRNA production and characterisation</li><li>LNP manufacture and characterisation</li><li>Conjugation with targeting antibodies</li><li>Cell culture and flowcytometry</li><li>Various immunological and biochemical assays</li><li>Statistical analysis of data</li><li>Communication skills</li><li>Project management</li></ul><p><strong>About MHRA</strong></p><p>The Medicines and Healthcare products Regulatory Agency is an executive agency of the Department of Health and Social Care in the United Kingdom, ensuring that healthcare products meet safety standards and contribute to public health through the effective regulation of medicines and medical devices, underpinned by science and research.</p><p><strong>About S&amp;R</strong></p><p>The Science and Research (S&amp;R) function is an operational group of the MHRA based at a state-of-the-art scientific facility in South Mimms Hertfordshire. We are a global leader in the characterisation, standardisation and control of biological medicines with the objective to deliver public health impact via world-leading science, research and innovation. The successful candidate will have the unique experience of undertaking the PhD research at a government facility.</p><p><strong>About the Teams</strong></p><p>The Immunotherapy team, within the Biotherapeutics and Advanced Therapies Team of S&amp;R, is a multi-skilled team with a range on expertise for investigating efficacy, safety and standardisation of biological medicines. The supervisor at UCL Department of Chemistry within the Faculty of Maths &amp; Physical Sciences, is an esteemed scientist leading interdisciplinary research across fields including optogenetics, organic synthesis, chemical biology and materials science. As part of the MHRA and UCL research community, the candidate will gain valuable opportunities for scientific development, collaboration and access to outstanding scientific expertise within both these institutions.</p><p><strong>Awarding Institution</strong></p><p>The successful candidate will be registered with the Department of Chemistry within the Faculty of Maths &amp; Physical Sciences at University College London, one of the UK's top research Universities, a global leader and a centre for teaching and research excellence. UCL Chemistry is recognised as one of the leading chemistry departments in the United Kingdom, ranking second nationally for research impact. Researchers at UCL contribute significantly to advancements across the field, from drug discovery to space exploration, driving key developments in contemporary chemistry.</p><h4>Person specification</h4><p><strong>About You</strong></p><p>Eligible students will be expected to hold an MSci (at least a 2:1) or a BSc (at least a merit) + MSc (at least a 2:1) or the international equivalents of the relevant first degree and the Masters’ degree. Additional relevant postgraduate or other laboratory work experience relating to the proposed project would be appreciated but not essential.</p><p>Please note, this studentship is only available to home students meeting the following criteria:</p><ul><li>Be a UK National (meeting residency requirements), or</li><li>Have settled status, or</li><li>Have pre-settled status (meeting residency requirements), or</li><li>Have indefinite leave to remain or enter</li></ul><p>The candidate will be a motivated individual with a passion for wanting to improve patient outcomes. You will have a keen interest in undertaking research in the fields of immunotherapy and immunology with a focus on engineering and characterisation of novel emerging therapies.</p><p>Your key responsibilities will be:</p><p>- To undertake the research projects in line with the project aims.</p><p>- To communicate effectively, orally and through written media, undertake presentations at scientific meetings and maintain excellent records.</p><p>- To interact regularly and effectively with your supervisors and interact appropriately and effectively with other staff.</p><ul><li>To meet the expectations of the study for a PhD by the awarding body (University).</li></ul><h4>Benefits</h4>Alongside your salary of £22,780, Medicines and Healthcare Products Regulatory Agency contributes £6,599 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p><strong>How to Apply</strong></p><p>Applications must include a CV, personal statement; detailing what you can bring to the project and what you would anticipate achieving from the studentship and the contact details of two referees. Applications should be e-mailed to the MHRA PhD Studentship office at <a href="mailto:studentship@nibsc.org" target="_blank">studentship@nibsc.org</a>. Please quote the relevant reference number in your letter. Informal enquiries can be made to Dr Deepa Rajagopal at <a href="mailto:deepa.rajagopal@mhra.gov.uk" target="_blank">deepa.rajagopal@mhra.gov.uk</a>. </p><p>If you have a disability defined by the Equality Act 2010 (<a href="https://www.gov.uk/definition-of-disability-under-equality-act-2010" target="_blank">https://www.gov.uk/definition-of-disability-under-equality-act-2010</a>) you may apply under the UK Civil Service Guaranteed Interview Scheme provided that you meet all of the qualifications, skills, requirements and experience defined as essential for the studentship. You must submit the Guaranteed Interview Scheme Declaration form with your application: this can be found at <a href="https://www.gov.uk/government/publications/guaranteed-interview-scheme." target="_blank">https://www.gov.uk/government/publications/guaranteed-interview-scheme.</a> At interview all applicants will be assessed solely on merit.</p><p>UCL actively supports equality, diversity and inclusion and encourages applications from all sections of society. We strongly encourage applications from those who are currently under-represented within our research student community: BAME British applicants, applicants with disabilities and older applicants.</p><p>Any offer of a studentship is conditional upon successful background screening which includes, but is not limited to checks on identity, qualifications and right to study in the UK, as well as formal approval by UCL on the UCL Research: degree Chemistry programme.</p><p><em>Subject areas: Immunology, immunotherapy, mRNA vaccines, CAR T-cell engineering</em></p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:deepa.rajagopal@mhra.gov.uk" target="_blank">deepa.rajagopal@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

PhD Studentship - Immunotherapy

<h4>Job summary</h4><p><strong>Funding notes</strong></p><p>The studentship is fully funded for 4 years but is only available for students eligible for home UK fees. Entry requirements are a first class BSc degree or a 2:1 (or international equivalent). An MSc in a relevant subject (or international equivalent) is also acceptable. Imperial College London actively supports equality, diversity and inclusion and encourages applications from all sections of society. We strongly encourage applications from those who are currently under-represented within our research student community: BAME British applicants, applicants from working class backgrounds, applicants with disabilities and older applicants.</p><p><strong>Project description</strong></p><p>A 4-year full-time PhD studentship is available in the Vaccines Team, working with the Biotherapeutics and Advanced Therapies Team of the Medicines and Healthcare Products Regulatory Agency (MHRA). This project is in collaboration with the Department of Infectious Disease at Imperial College London. The student will also be required to complete two 3-month rotations in the wider MHRA within their first year allowing them to gain insight into public health research.</p><p>The project will be supervised by Dr Othmar Engelhardt and Dr Simon Hufton at MHRA and Prof John Tregoning at Imperial College London. The studentship is anticipated to commence on 1st October 2026. The studentship will offer a stipend, currently £22,780 per year and reviewed annually. </p><h4>Job description</h4><p><strong>About the Project</strong></p><p>Respiratory Syncytial Virus (RSV) causes significant disease burden, particularly in the very young and the very old. Recently there has been progress in preventing this virus, with the licensing of three vaccines and two monoclonal antibodies (mAbs Nirsevimab (Beyfortus) and Clesrovimab (MK-1654)). The success or failure of both antibodies and vaccines for RSV depends upon virus evolution and escape; this will particularly impact monoclonal antibodies. Another concern is that RSV immunisation may cause replacement of its ecological niche by the related winter virus human metapneumovirus (hMPV), itself a high priority amongst vaccine developers. An estimated 473,000 hMPV-associated hospitalisations occur globally, of which 185,000 were in high-income countries.</p><p>Hypothesis: Nanobodies that are cross-neutralising for RSV and hMPV can be generated.</p><p>The student will focus on the following topics:</p><ul><li>Generation of mRNA and proteins for pre-F from RSV and hMPV for immunisation. <ul><li>Based on the design of stabilised RSV pre-fusion F protein constructs and matching RNA vaccines developed by the Tregoning lab, the student will generate matching hMPV proteins and constructs.</li></ul></li><li>Immunisation of alpacas to recover nanobodies. <ul><li>Nanobody libraries will be generated from the immunised alpacas and appropriate selection strategies will be developed and employed to isolate cross-reactive nanobodies binding F protein of RSV and hMPV.</li></ul></li><li>Characterisation of nanobodies. <ul><li>Isolated nanobodies will be expressed in bacteria and characterised for binding (e.g., by ELISA or surface plasmon resonance). Their ability to neutralise RSV and hMPV will be assessed.</li></ul></li><li>Identification of escape mutants. <ul><li>Using classical virology techniques, RSV and hMPV viruses will be selected that escape neutralisation by the lead nanobodies. Escape mutants will be sequenced, thereby providing information about the epitopes recognised by the nanobodies.</li><li>The student will also model, using computational approaches, the identified amino acid changes on the respective F proteins, enhancing our knowledge about mutational tolerance of the F protein and the nanobody-binding interface.</li></ul></li><li>Testing of nanobodies in vivo as potential therapeutic agents. <ul><li>Using well established RSV challenge models, the student will explore protection against infection. This will be performed both prophylactically and therapeutically.</li></ul></li></ul><p>This is a multi-disciplinary project involving virology, biochemistry and molecular biology.</p><p><strong>About MHRA</strong></p><p>The Medicines and Healthcare products Regulatory Agency is an executive agency of the Department of Health and Social Care in the United Kingdom, ensuring that healthcare products meet safety standards and contribute to public health through the effective regulation of medicines and medical devices, underpinned by science and research.</p><p><strong>About S&amp;R</strong></p><p>The Science and Research (S&amp;R) function is an operational group of the MHRA based at a state-of-the-art scientific facility in South Mimms Hertfordshire. We are a global leader in the characterisation, standardisation and control of biological medicines with the objective to deliver public health impact via world-leading science, research and innovation. The successful candidate will have the unique experience of undertaking the PhD research at a government facility.</p><p><strong>About the Teams</strong></p><p>The Influenza Resource Centre (IRC) within the Vaccines team is responsible for the research and development that underpins the selection of influenza candidate vaccine viruses, vaccine potency assay reagents and influenza vaccine control testing and has been involved in the standardisation of RSV serology assays. The Biotherapeutics and Advanced therapies team is responsible for the safety and efficacy of biotherapeutic medicines. Professor Tregoning’s research group is based in the Department of Infectious Disease at the South Kensington campus of Imperial.</p><p><strong>Awarding Institution</strong></p><p>The successful candidate will be registered with the Department of Infectious Disease at Imperial College London, one of the UK's top research Universities. Research in the department spans both viral and bacterial pathogens, exploring fundamental biology as well as developing vaccines, antibodies and therapeutics.</p><h4>Person specification</h4><p><strong>About You</strong></p><p>As a candidate you will be a motivated individual, wanting to improve patient outcomes. You will have a keen interest in undertaking research in the fields of virology and immunology with a focus on antiviral therapy.</p><p>Applicants must hold (or obtain by Oct 2026) a first or upper-second-class honours degree or equivalent in a Life Sciences or health‐related discipline. A Master’s degree in immunology or a related field is desirable or equivalent research experience. Prior experience in bioinformatics is desirable but not essential. Applicants must also meet Imperial College’s English language requirements – further details can be found at <a href="https://www.findaphd.com/common/clickCount.aspx?theid=193146&amp;type=184&amp;DID=3425&amp;url=https%3a%2f%2fwww.imperial.ac.uk%2fstudy%2fpg%2fapply%2frequirements%2fenglish%2f" target="_blank">https://www.imperial.ac.uk/study/pg/apply/requirements/english/</a>.</p><p>Please note, this studentship is only available to home students who meet the following criteria:</p><ul><li>Be a UK National (meeting residency requirements), or</li><li>Have settled status, or</li><li>Have pre-settled status (meeting residency requirements), or</li><li>Have indefinite leave to remain or enter</li></ul><p>Your key responsibilities will be:</p><ul><li>To undertake the research projects in line with the project aims.</li><li>To communicate effectively, orally and through written media, undertake presentations at scientific meetings and maintain excellent records.</li><li>To interact regularly and effectively with your supervisors and interact appropriately and effectively with other staff.</li><li>To meet the expectations of the study for a PhD by the awarding body (university).</li></ul><h4>Benefits</h4>Alongside your salary of £22,780, Medicines and Healthcare Products Regulatory Agency contributes £6,599 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p><strong>How to Apply</strong></p><p>Please send a CV and personal statement detailing what you can bring to the project and what you would anticipate achieving from the studentship and the contact details of two referees to the MHRA PhD Studentship office at <a href="mailto:studentship@mhra.org" target="_blank">studentship@mhra.org</a> . Please quote MHRA-PhD-1-2025 in your letter. Informal enquiries can be made to Dr Othmar Engelhardt at <a href="mailto:othmar.engelhardt@mhra.gov.uk" target="_blank">othmar.engelhardt@mhra.gov.uk</a>.</p><p>If you have a disability defined by the Equality Act 2010 (<a href="https://www.gov.uk/definition-of-disability-under-equality-act-2010" target="_blank">https://www.gov.uk/definition-of-disability-under-equality-act-2010</a>) you may apply under the UK Civil Service Guaranteed Interview Scheme provided that you meet all of the qualifications, skills, requirements and experience defined as essential for the studentship. You must submit the Guaranteed Interview Scheme Declaration form with your application: this can be found at <a href="https://www.gov.uk/government/publications/guaranteed-interview-scheme." target="_blank">https://www.gov.uk/government/publications/guaranteed-interview-scheme.</a> At interview all applicants will be assessed solely on merit.</p><p>Any offer of a studentship is conditional upon successful background screening which includes, but is not limited to checks on identity, qualifications and right to study in the UK.</p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:othmar.engelhardt@mhra.gov.uk" target="_blank">othmar.engelhardt@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

PhD Studentship - Seasonal Influenza

<h4>Job summary</h4><p><strong>Funding notes</strong></p><p>The studentship is only available for students eligible for home UK fees. Entry requirements are a first-class BSc degree or a 2:1 (or international equivalent). An MSc in a relevant subject (or international equivalent) is also acceptable. University of Reading actively supports equality, diversity and inclusion and encourages applications from all sections of society. We strongly encourage applications from those who are currently under-represented within our research student community: BAME British applicants, applicants with disabilities and older applicants. </p><p>As a candidate, you will be a highly motivated individual interested in undertaking research in the field of cell and molecular biology.</p><p><strong>Project description</strong></p><p>A 4-year full-time PhD studentship is available in the Immunohaematology &amp; Autoimmunity team, working with the Standards Lifecycle within the Science and Research operational group (S&amp;R) of the Medicines and Healthcare products Regulatory Agency (MHRA). This project is in collaboration with the Institute for Cardiovascular and Metabolic Research (ICMR), School of Biological Sciences, at University of Reading. The student will also be required to complete two 3-month rotations in the wider MHRA within their first year allowing them to gain insight into public health research.</p><p>The project will be supervised by Dr Dina Vara at the MHRA, and by Prof Jon Gibbins and Dr Chris Jones at the University of Reading. The studentship is anticipated to commence on 28th September 2026. The studentship will offer a stipend, currently £22,780 per year and reviewed annually. </p><h4>Job description</h4><p><strong>About the Project</strong></p><p>Platelet transfusion is essential for the management of bleeding, trauma, and thrombocytopenia, yet reliance on short-lived, fresh platelets poses major logistical and clinical challenges. Lyophilised platelets (LPs) have been explored as a potential alternative since the mid-20th century, yet uncertainties remain regarding the extent to which platelet structure, function, and metabolic activity are preserved following freeze-drying.</p><p>Recent studies, alongside earlier exploratory work, suggest that trehalose-loaded lyophilised platelets (TL-LPs) can retain key haemostatic properties. However, the mechanisms underpinning this preservation and the degree to which TL-LPs recapitulate the structural and functional characteristics of fresh platelets remain insufficiently defined. Addressing these knowledge gaps is essential for advancing TL-LPs towards therapeutic, diagnostic, and quality-control applications.</p><p>This multidisciplinary PhD project aims to systematically investigate the impact of lyophilisation on platelet structure and function, with a particular focus on membrane integrity, haemostatic activity, mitochondrial stability, and long-term storage resilience. By building on emerging evidence in platelet preservation and biostabilisation, the project seeks to establish whether TL-LPs retain sufficient platelet-like properties to support their clinical translation.</p><p>The proposed research will assess the feasibility of using TL-LPs as functional platelet surrogates through comprehensive in vitro evaluation. Specific objectives include: (i) characterisation of membrane architecture and preservation of key platelet surface receptors following lyophilisation; (ii) evaluation of primary and secondary haemostatic function; (iii) assessment of mitochondrial integrity and metabolic responsiveness; and (iv) determination of TL-LP stability under varying storage durations and environmental conditions.</p><p>The successful candidate will gain extensive training in a wide range of laboratory techniques relevant to platelet biology, haemostasis, and biotherapeutic development. These will include advanced microscopy, flow cytometry, functional haemostasis assays, metabolic and mitochondrial analyses, and data interpretation using appropriate statistical approaches. As with all PhD projects, experimental strategies will be refined as the project develops, and new findings emerge.</p><p>The student will benefit from multidisciplinary supervision and access to state-of-the-art facilities across the University of Reading and the MHRA, providing a unique translational research environment at the interface of academic science and regulatory science. In addition, the candidate will have access to specialised training courses and professional development opportunities and will be encouraged to present their findings at national and international scientific conferences.</p><p><strong>About MHRA</strong></p><p>The Medicines and Healthcare products Regulatory Agency enhances and improves the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.</p><p><strong>About S&amp;R</strong></p><p>Based at a state-of-the-art scientific facility in South Mimms Hertfordshire, S&amp;R is an operational group of the MHRA. We are a global leader in the characterisation, standardisation and control of biological medicines with the objective to deliver public health impact via world-leading science, research and innovation. The successful candidate will have the unique experience of undertaking the PhD research at a government facility.</p><p><strong>About the Team</strong></p><p>The Immunohaematology and Autoimmunity team, within the Standards Lifecycle division of S&amp;R, is an expert group focused on developing lyophilised biological products that support World Health Organization International Standards.</p><p><strong>Awarding Institution</strong></p><p>The successful candidate will be registered at the School of Biological Sciences, University of Reading — a leading UK research centre in cardiovascular and platelet biology, recognised for its expertise in thrombosis, haemostasis and related fields.</p><h4>Person specification</h4><p><strong>About You</strong></p><p>Eligible students will be expected to hold an MSci (at least a 2:1) or a BSc (at least a merit) + MSc (at least a 2:1) or the international equivalents of the relevant first degree and the Masters’ degree. Additional relevant postgraduate or other laboratory work experience relating to the proposed project would be appreciated but not essential.</p><p>Please note, this studentship is only available to home students meeting the following criteria:</p><ul><li>Be a UK National (meeting residency requirements), or</li><li>Have settled status, or</li><li>Have pre-settled status (meeting residency requirements), or</li><li>Have indefinite leave to remain or enter</li></ul><p>As a candidate, you will be a motivated individual with a strong passion for improving patient outcomes. You will have a keen interest in working with the Standards Lifecycle within the Science and Research operational group (S&amp;R) of the Medicines and Healthcare products Regulatory Agency (MHRA).</p><p>Your key responsibilities will be:</p><ul><li>To undertake the research projects in line with the project aims.</li><li>To communicate effectively, orally and through written media, undertake presentations at scientific meetings and maintain excellent records.</li><li>To interact regularly and effectively with your supervisors and interact appropriately and effectively with other staff.</li><li>To meet the expectations of the study for a PhD by the awarding body (University).</li></ul><h4>Benefits</h4>Alongside your salary of £22,780, Medicines and Healthcare Products Regulatory Agency contributes £6,599 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p><strong>How to Apply</strong></p><p>You should submit a covering letter, with your application and CV, detailing what you can bring to the project and what you would anticipate achieving from the studentship to <a href="mailto:studentship@nibsc.org" target="_blank">studentship@mhra.gov.uk</a> Please quote the reference number MHRA-PhD-2-2025 in your letter. Informal enquiries can be directed to <a href="mailto:dina.vara@mhra.gov.uk" target="_blank">dina.vara@mhra.gov.uk</a>.</p><p>If you have a disability defined by the Equality Act 2010 (<a href="https://www.gov.uk/definition-of-disability-under-equality-act-2010" target="_blank">https://www.gov.uk/definition-of-disability-under-equality-act-2010</a>) you may apply under the UK Civil Service Guaranteed Interview Scheme provided that you meet all of the qualifications, skills, requirements and experience defined as essential for the studentship. You must submit the Guaranteed Interview Scheme Declaration form with your application: this can be found at <a href="https://www.gov.uk/government/publications/guaranteed-interview-scheme." target="_blank">https://www.gov.uk/government/publications/guaranteed-interview-scheme.</a> At interview all applicants will be assessed solely on merit.</p><p>Any offer of a studentship is conditional upon successful background screening which includes, but is not limited to checks on identity, qualifications and right to study in the UK.</p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:dina.vara@mhra.gov.uk" target="_blank">dina.vara@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

PhD Studentship - Therapeutic Reference Materials

<h4>Job summary</h4><p>We are currently looking for a <strong>Head of Gene Therapy</strong> to join our <strong>Biotherapeutics and Advanced Therapies </strong>Function within the <strong>Research and Development </strong>group. </p><p>This is a <strong>full-time</strong> opportunity, on a <strong>fixed term contract </strong>basis until 19th February 2027. The role will be based in South Mimms, Hertfordshire. </p><p><strong>Who are we?</strong></p><p>The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. </p><p>The research and development function of the MHRA Science Campus comprises a multi-disciplinary team of internationally respected scientists who deliver strategically aligned regulatory scientific research focused on the development and distribution of biological reference materials. </p><p>The Gene Therapy team aims to impact the future safety and quality of gene therapies through addressing regulatory focused research questions and by driving the global harmonisation of gene therapy critical quality attribute assessment, underpinned by the development and application of new physical standards. <br></p><p><strong>What’s the role?</strong></p><p>This post has the global role of developing and executing a programme of research &amp; development for the standardisation and safety of gene therapy medicines. The post-holder is expected to deliver on existing projects, to actively contribute to other ongoing gene therapy projects across the group and to support the development of new projects through applications for externally funded research projects. </p><p>The role will lead a team of expert scientists to address prioritised regulatory scientific research focused on the safety, characterisation and accelerated regulatory approval of gene therapy medicines. </p><p>The role will establish and foster strategically important National and International research collaborations and will also liaise closely with scientists in Standards Lifecycle and Control Testing Functions as well as licensing colleagues in HQA and Safety and Surveillance Divisions. Aligned to effective communication and collaboration, the postholder will apply their highly specialist scientific knowledge in gene therapy products to improve efficiencies and optimise Agency activities to bring new and innovative medicines to UK patients. </p><h4>Job description</h4><p><strong>Key responsibilities:</strong></p><ul><li>Contribute to the development of a research portfolio of projects related to the standardisation and safety of gene therapy medicines and build up capability and resilience in future gene therapy standardisation area. </li></ul><ul><li>Initiate and drive gene therapy research activities, which result in scientific data that is publishable in high quality scientific journals and attracts sustained external grant funding. Identify potential sources of income generation and apply for external grant funding for specialist projects. </li></ul><ul><li>Assure that project deliverables and internal objectives are met. Undertake general project administration for the projects, including financial monitoring and reporting. Monitor the effectiveness of the activities, identify areas of improvement and support implementation of new policies. </li></ul><ul><li>Maintain and disseminate up-to-date knowledge around gene therapy research and standardisation. Work with the national and international gene therapy community to develop and disseminate good practices. Represent the Group and the Agency at national and international conferences and other relevant meetings/workgroups as appropriate. </li></ul><ul><li>Work within the required quality framework (e.g. ISO 13485, ISO 34). Write, review and maintain quality records, including the generation of production records and reports, standard operating procedures, COSHH and risk assessments. </li></ul><ul><li>Work closely and communicate effectively with Agency colleagues as required (including Standards Lifecycle, British Pharmacopeia and Licensing) to provide expert scientific advice and practical support as well as with external collaborators. </li></ul><p><strong>Who are we looking for?</strong></p><p>Our successful candidate will have: </p><ul><li>PhD in molecular biology, virology, genetics or immunology, with strong and relevant post-doctoral experience </li></ul><ul><li>Extensive experience in gene therapy, molecular biology, virology, genetics and immunology </li></ul><ul><li>Experience or interest in standardisation, medicines control and working under a Quality Management System </li></ul><ul><li>Experience in developing and applying innovative technical procedures for product potency and efficacy quality control </li></ul><ul><li>Internationally competitive track record in gene therapy research and development and experience of securing resources </li></ul><h4>Person specification</h4><p><strong>Method of assessment: A=Application, I=Interview, P=Presentation </strong></p><p><strong>Behaviour Criteria:</strong></p><ul><li>Delivering at Pace <strong>(A, I)</strong></li></ul><ul><li>Working Together <strong>(A, I)</strong></li></ul><ul><li>Communicating and Influencing <strong>(I)</strong></li></ul><p><strong>Experience Criteria:</strong></p><ul><li>Extensive experience in gene therapy, molecular biology, virology, genetics, and immunology <strong>(A, I, P)</strong></li></ul><ul><li>Experience in developing and applying innovative technical procedures for product potency and efficacy quality control <strong>(I, P)</strong></li></ul><ul><li>Internationally competitive track record in gene therapy research and development and experience of securing resources <strong>(A)</strong></li></ul><ul><li>Experience or interest in standardisation and medicines control and in working under a Quality Management System <strong>(A, I)</strong></li></ul><ul><li>In-depth practical experience in a broad range of relevant biological laboratory techniques, including cell culture and molecular biology <strong>(I, P)</strong></li></ul><p><strong>Technical Criteria:</strong></p><ul><li>PhD in molecular biology, virology, genetics or immunology, with strong and relevant post-doctoral experience <strong>(A, I, P)</strong></li></ul><p><strong>Strengths Criteria</strong></p><ul><li>Analytical <strong>(I)</strong></li></ul><p>If you would like to find out more about this fantastic opportunity, <a href="https://mhra-gov.filecamp.com/uniq/gYBShDPeqCdGqcV3.pdf" target="_blank">please read our Job Description and Person Specification</a>! </p><p><strong><em>Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact </em></strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong><em>careers@mhra.gov.uk</em></strong></a></p><h4>Benefits</h4>Alongside your salary of £60,778, Medicines and Healthcare Products Regulatory Agency contributes £17,607 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p>We use the Civil Service Success Profiles to assess our candidates, <a href="https://www.gov.uk/government/publications/success-profiles" target="_blank">find out more here</a>. </p><ul><li>Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. <em>Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.</em></li></ul><ul><li>Presentation, to be prepared as part of your interview, with further information being supplied when you reach this stage. </li></ul><ul><li>Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. </li></ul><p>In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of <strong>Experience or interest in standardisation and medicines control and in working under a Quality Management System</strong><strong>.</strong></p><p><strong>If you require any disability related adjustments at any point during the process, please contact </strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong>careers@mhra.gov.uk</strong></a><strong> as soon as possible.</strong></p><p>Closing date: 26th January </p><p>Shortlisting date: from 2nd February </p><p>Interview date: from 16th February </p><p>If you need assistance applying for this role or have any other questions, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a></p><p>Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available <a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">here</a>. </p><p>Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard?_ga=2.149328757.2118900794.1613132232-433185063.1580991281" target="_blank">basic personnel security standard checks</a>. </p><p>Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include: </p><ul><li>Laboratory-based roles working directly with known pathogens </li></ul><ul><li>Maintenance roles, particularly those required to work in laboratory settings </li></ul><ul><li>Roles that involve visiting other establishments where vaccination is required </li></ul><ul><li>Roles required to travel overseas where specific vaccination may be required. </li></ul><p>Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government. </p><p>Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility <a href="https://www.childcarechoices.gov.uk/" target="_blank">here</a>. </p><p>Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a>. </p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

Head of Therapy - £60,778 p.a. + benefits

Higher Scientist - Global Specialised Polio Laboratory - £37,456 p.a. + benefits

<h4>Job summary</h4><p>We are currently looking for a <strong>Senior Scientist AI Genomics </strong>to join our <strong>Research and Development</strong> Function within the <strong>Science and Research</strong> group. </p><p>This is a <strong>full-time</strong> opportunity, on a <strong>permanent </strong>basis. The role will be based in South Mimms, Hertfordshire. </p><p>Government departments and agencies are working towards implementing a minimum 60% attendance in office sites. </p><p>We are currently implementing a flexible, hybrid way of working, with a minimum of 8 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business. Attendance on site is driven by business needs so depending on the nature of the role, this can flex up as required, with the remainder of time worked either remotely or in the office. Some roles will need to be on site more regularly.</p><p><strong>Who are we?</strong></p><p>The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. </p><p>The Science and Research Group delivers public health impact, world-leading research innovation, and a unique proposition via an ambitious Science Strategy which will balance innovation against sustainability and affordability. </p><p>The S&amp;R Research &amp; Development function will deliver statutory mandated strategically aligned, sustainable and impactful Regulatory Scientific research that is applied primarily to biological reference materials development and medicines control testing and areas of international and national priority for extant and future biological medicines. Research and Development will host and nurture the current excellence in research into biologicals, biological reference materials, biological activity measurements, product quality testing and standardisation that was formerly hosted by the National Institute for Biological Standards and Control (NIBSC). </p><h4>Job description</h4><p><strong>What’s the role?</strong></p><p>The post-holder will be responsible for: </p><ul><li>Leading the design and evaluation of AI/ML models applied to genomic, clinical, and multi-modal datasets, ensuring their safety, transparency, and performance for regulatory and healthcare applications. </li></ul><ul><li>Providing deep expertise in generative AI and advanced bioinformatics to support the Genomics team in its mission to accelerate the harmonisation of genomic diagnostics across the UK and internationally. </li></ul><ul><li>Collaborating with leading researchers across multiple institutions, fostering innovation and working within the UK genomics ecosystem, including the NHS, academia, AI labs, and bioinformatics networks, to shape standards for next-generation diagnostics, precision medicine, and AI-driven clinical genomics. </li></ul><p><strong>Key responsibilities:</strong></p><ul><li>Lead the design, development, and implementation of cutting-edge generative AI tools and advanced bioinformatics pipelines to support applications in genomic diagnostics. </li></ul><ul><li>Lead the development of innovative, fit-for-purpose synthetic genomic data standards for AI in genomics, to complement established physical international standards and reference materials. </li></ul><ul><li>Provide expert input into guidance documents, regulatory frameworks and validation approaches for AI-enabled diagnostic tools. </li></ul><ul><li>Contribute to national and international standards for AI in genomics, working with WHO, ISO, GA4GH and UK partners. </li></ul><p><strong>Who are we looking for?</strong></p><p>Our successful candidate will: </p><ul><li>Demonstrate experience in biological and clinical data analysis and across a range of NGS applications. </li></ul><ul><li>Demonstrate experience in generative AI tools and advanced bioinformatics pipelines to support applications in genomic diagnostics. </li></ul><ul><li>Have obtained a MS degree with 3+ years of experience or PhD in bioinformatics, computational biology, computer science, or related field. </li></ul><ul><li>Have a deep understanding of NGS data formats, bioinformatics tools, AI/ML models. </li></ul><ul><li>Be able to establish professional relationships with a range of stakeholders. </li></ul><h4>Person specification</h4><p><strong>Method of assessment: A=Application, I=Interview, P=Presentation </strong></p><p><strong>Behaviour Criteria:</strong></p><ul><li>Working Together <strong>(A, I)</strong></li></ul><ul><li>Delivering at Pace <strong>(A, I)</strong></li></ul><p><strong>Experience Criteria:</strong></p><ul><li>Demonstrated experience in biological and clinical data analysis and across a range of NGS applications <strong>(A, P)</strong></li></ul><ul><li>Demonstrated experience in generative AI tools and advanced bioinformatics pipelines to support applications in genomic diagnostics <strong>(A, I, P)</strong></li></ul><ul><li>Expertise in multi-modal data integration, including genomic, clinical, and biological datasets <strong>(A, I, P)</strong></li></ul><ul><li>Familiarity with regulatory policy development and horizon scanning for emerging AI technologies in healthcare <strong>(A, P)</strong></li></ul><ul><li>Strong knowledge of genomics, variant interpretation, clinical genetics and assay performance <strong>(A, P)</strong></li></ul><p><strong>Technical Criteria:</strong></p><ul><li>MS degree with 3+ years of experience or PhD in bioinformatics, computational biology, computer science, or related field <strong>(A, P)</strong></li></ul><ul><li>Deep understanding of NGS data formats, bioinformatics tools, AI/ML models <strong>(A, I, P)</strong></li></ul><p><strong>Strengths Criteria</strong></p><ul><li>Analytical <strong>(I)</strong></li></ul><ul><li>Learner <strong>(I)</strong></li></ul><p>If you would like to find out more about this fantastic opportunity, <a href="https://mhra-gov.filecamp.com/uniq/u5gjn02sOhfzXp2z.pdf" target="_blank">please read our Job Description and Person Specification</a>! </p><p><strong><em>Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact </em></strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong><em>careers@mhra.gov.uk</em></strong></a></p><h4>Benefits</h4>Alongside your salary of £46,160, Medicines and Healthcare Products Regulatory Agency contributes £13,372 towards you being a member of the Civil Service Defined Benefit Pension scheme. <a href="https://www.civilservicepensionscheme.org.uk/memberhub/joining-the-pension-scheme/benefits-of-the-pension-scheme/" target="_blank"> Find out what benefits a Civil Service Pension provides.</a><ul><li>Annual Leave: 25 days annual leave on entry, rising by one day for each completed year of service to a maximum of 30 days and pro-rata for part-time staff. PLUS 8 bank holidays </li><li>Privilege Leave: 1 day </li><li>Hours of Work: 37 hours (net) per week for full time staff in all geographical locations, including London and pro rata for part-time staff </li><li>Occupational Sick Pay (OSP): One month full pay/one month half pay on entry, rising by one month for each completed year of service to a maximum of five months full pay/five months half pay </li><li>Mobility: Mobility clause in contracts allowing staff to be mobile across the Civil Service </li><li>Civil Service Pension Scheme. Please see the link for further information <a href="http://www.civilservicepensionscheme.org.uk/" target="_blank">http://www.civilservicepensionscheme.org.uk/</a> For enquiries relating to the Civil Service Pension Schemes please contact MyCSP's Pension Service Centre directly on 0300 123 6666 </li><li>Flexible working to ensure staff maintain a healthy work-life balance </li><li>Interest free season ticket loan or bike loan </li><li>Employee Assistance Services and access to the Civil Service Benevolent Fund </li><li>Eligibility to join the Civil Service Motoring Association (CSMA) </li><li>Variety of staff and Civil Service clubs </li><li>On-going learning and development </li></ul><h4>Things you need to know</h4><h4>Artificial intelligence</h4>Artificial intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our <a href="https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/" target="_blank">candidate guidance (opens in a new window)</a> for more information on appropriate and inappropriate use.<h4>Selection process details</h4><p>We use the Civil Service Success Profiles to assess our candidates, <a href="https://www.gov.uk/government/publications/success-profiles" target="_blank">find out more here</a>. </p><ul><li>Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. <em>Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.</em></li></ul><ul><li>Presentation, to be prepared as part of your interview, with further information being supplied when you reach this stage. </li></ul><ul><li>Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. </li></ul><p>In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of <strong>Demonstrated experience in generative AI tools and advanced bioinformatics pipelines to support applications in genomic diagnostics</strong> and <strong>Deep understanding of NGS data formats, bioinformatics tools, AI/ML models</strong>. </p><p><strong>If you require any disability related adjustments at any point during the process, please contact </strong><a href="mailto:careers@mhra.gov.uk" target="_blank"><strong>careers@mhra.gov.uk</strong></a><strong> as soon as possible.</strong></p><p>Closing date: 30th January </p><p>Shortlisting date: from 6th February </p><p>Interview date: from 16th February </p><p>If you need assistance applying for this role or have any other questions, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a></p><p>Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available <a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">here</a>. </p><p>Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard?_ga=2.149328757.2118900794.1613132232-433185063.1580991281" target="_blank">basic personnel security standard checks</a>. </p><p>Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include: </p><ul><li>Laboratory-based roles working directly with known pathogens </li></ul><ul><li>Maintenance roles, particularly those required to work in laboratory settings </li></ul><ul><li>Roles that involve visiting other establishments where vaccination is required </li></ul><ul><li>Roles required to travel overseas where specific vaccination may be required. </li></ul><p>Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government. </p><p>Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility <a href="https://www.childcarechoices.gov.uk/" target="_blank">here</a>. </p><p>Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a>. </p><p>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, in the first instance, you should contact the MHRA Recruitment Team at <a href="mailto:careers@mhra.gov.uk" target="_blank">careers@mhra.gov.uk</a>. </p><p>If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: <a href="https://civilservicecommission.independent.gov.uk/" target="_blank">civilservicecommission.independent.gov.uk</a></p><p><a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a></p><p>Civil Service Commission </p><p>Room G/8 </p><p>1 Horse Guards Road </p><p>London </p><p>SW1A 2HQ </p><br><br>Feedback will only be provided if you attend an interview or assessment.<h4>Security</h4>Successful candidates must undergo a criminal record check.People working with government assets must complete <a href="https://www.gov.uk/government/publications/government-baseline-personnel-security-standard" target="_blank">baseline personnel security standard (opens in new window)</a> checks.<h4>Nationality requirements</h4><p>This job is broadly open to the following groups:</p><ul><li>UK nationals</li><li>nationals of the Republic of Ireland</li><li>nationals of Commonwealth countries who have the right to work in the UK</li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the <a href="https://www.gov.uk/settled-status-eu-citizens-families" target="_blank">European Union Settlement Scheme (EUSS) (opens in a new window)</a></li><li>nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)</li><li>individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020</li><li>Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service</li></ul><a href="https://www.gov.uk/government/publications/nationality-rules" target="_blank">Further information on nationality requirements (opens in a new window)</a><h4>Working for the Civil Service</h4>The <a href="http://civilservicecommission.independent.gov.uk/code/" target="_blank">Civil Service Code (opens in a new window)</a> sets out the standards of behaviour expected of civil servants.<br><br>We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's <a href="https://civilservicecommission.independent.gov.uk/recruitment/recruitment-principles/" target="_blank">recruitment principles (opens in a new window)</a>.The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme (DCS) for candidates with disabilities who meet the minimum selection criteria.The Civil Service also offers a Redeployment Interview Scheme to civil servants who are at risk of redundancy, and who meet the minimum requirements for the advertised vacancy.<h4>Diversity and Inclusion</h4>The Civil Service is committed to attract, retain and invest in talent wherever it is found. To learn more please see the<a href="https://www.gov.uk/government/publications/civil-service-people-plan-2024-2027/civil-service-people-plan-2024-2027-html" target="_blank">Civil Service People Plan (opens in a new window)</a> and the <a href="https://www.gov.uk/government/publications/civil-service-diversity-and-inclusion-strategy-2022-to-2025" target="_blank">Civil Service Diversity and Inclusion Strategy (opens in a new window)</a>.<h4>Apply and further information</h4>Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.<h4>Contact point for applicants</h4><h4>Job contact : </h4><ul><li>Name : The Resourcing Team</li><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Recruitment team</h4><ul><li>Email : <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a></li></ul><h4>Further information</h4>In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, you should contact the Resourcing Team at <a href="mailto:Careers@mhra.gov.uk" target="_blank">Careers@mhra.gov.uk</a>, in the first instance. If you are not satisfied with the response you receive you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk - <a href="mailto:info@csc.gov.uk" target="_blank">info@csc.gov.uk</a> - Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ<br><br>

Senior Scientist AI Genomics - £46,160 p.a. + benefits

<ul><li><a href="https://feeds.jgp.co.uk/public_data/VacancyDocuments/0076/6763/Refuse_Recycling_Loader__C__see_JD_for_post_nos_.docx" target="_blank">Refuse_Recycling_Loader__C__see_JD_for_post_nos_</a></li>
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<p>Please apply on line via the link provided</p>



<p>Hertsmere Borough Council are looking for Refuse/ Recycling Loaders, to join our efficient street cleansing, waste and recycling collection service within and around Hertsmere.</p>
<p>The job involves collecting all types of refuse and recycling waste, from litter bins, residential bins and trade bins, and loading them into the refuse vehicle.&nbsp; You will need to have excellent fitness levels and be capable of walking for 8 to 12 miles per day.</p>
<p>You will need proven experience of heavy manual work involving lifting, and be capable of pulling and emptying refuse bins.&nbsp; You should have a customer service approach to service delivery, communicating positively and working efficiently in a team.&nbsp; You should be self-motivated and able to work without close supervision.</p>
<p>This post is offered on a full time, temporary contract, via an agency.</p>
<p>To apply, please contact one of the following agencies:</p>
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<li>Extra staff: 07810 883716 - <a href="mailto:conrad.eaton@extrastaff.com" target="_blank">conrad.eaton@extrastaff.com</a>
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<li>GOT People: 01923 882 888 or 07557 742 138 – <a href="mailto:Kjackson@gotpeople.co.uk" target="_blank">Kjackson@gotpeople.co.uk</a>
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<li>FirstCall: 01992 635 363 or 07710 089 373 – <a href="mailto:wioleta.wanat-sarna@firstcallcontractservices.co.uk" target="_blank">wanat-sarna@firstcallcontractservices.co.uk</a>
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<p><strong>(The agency you approach will confirm their pay rate.)</strong></p>
<p><strong>Closing date for applications: Ongoing recruitment until 31st March 2026</strong></p>

10 Jobs in Potters Bar, UK